Ihor> Can you: 1. Load your agenda 2. Start 'cpu+mem profiler 3. Rebuild the agenda 4. Share the
    Ihor> obtained 'cpu _and_ 'mem reports

I found an issue.
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void-function org-looking-at
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    Ihor> native-comp is improving things proportionally. It should actually have higher impact on
    Ihor> lower-end machine. I recommend native-comp unless you update frequently (and hence need to
    Ihor> re-compile using native-comp often).

On my case. My distro which is archlinux-arm aka alarm for 32bits does
not provide the compiled package libgccjit. So compiling it takes
several hours on this little machine. cross-compiling it takes almost
1h, but preparing the machine for cross-compilation takes time also. So
my conclusion is 'it does not worth the hassle'.